AIMAN INAM LONDON: Researchers here have discovered an enzyme that might prove helpful in defending people against scores of degenerative intellect sickness, particularly Alzheimer’s. Senior study researcher from Indiana University in the US, Professor Hui-Chen Lu noted, “This study has found that NMNAT2, or nicotinamide mononucleotide adenylyl transferase 2, is a key neuronal maintenance factor.” Lu further added, “It exerts both an enzyme function to protect neurons from stress caused by over-excitation, and a ‘chaperone’ function, shown for the first time in this study, to combat the proteins encountered by the brain during ageing.” Countless neurodegenerative disarrays are triggered through accretion of proteins in the head. Such circumstances known as proteinopathies, happen when proteins misfold, causing them to develop oppressive and bunch up in the brain in a shape frequently referred to as plaques, or tangles. In addition, NMNAT2 connects to misfolded proteins to thwart or fix the faults, which generate these clusters. Common proteinopathies include Alzheimer’s, Parkinson’s and Huntington’s ailments, plus amyotrophic lateral sclerosis ALS, which is also known as Lou Gehrig’s Disease.
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Source: News Pakistan